Lung Health Cohort (Healthy Volunteers)

Purpose of this Study

We are doing this study to find out why some young adults have better lung function than others during the period of peak lung health (ages 25 to 35 years old) for most people. We want to learn how people's actions or exposures can affect lung function and risk of future lung disease. These factors might include smoking, vaping or diet and environmental exposures to pollution and allergens.

Who Can Participate?

Eligibility

Adults ages 25-35 who:
- Are in general good health
- Are not pregnant
- Have never been diagnosed with cancer or heart disease

For more information about who can join this study, please contact the study team at DukeAirwayResearch@duke.edu or 919-479-0861.

Age Range

25-35

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes

What is Involved?

If you choose to join this study, you will:
- Visit our clinic 1 time
- Have images taken of your lungs (CT scan), possibly on a different date from the clinic visit
- Have your lung function tested
- Give blood, nasal swab, and urine samples
- Answer questionnaires
- Wear an activity monitor for 7 days
- Keep a study diary for the 7 days you use the activity monitor
- Keep a vaping diary for the 7 days of activity monitoring (only if you vape)

After your clinic visit, you will have 5 brief, virtual visits with the study team. A team member will coach you on how to perform some breathing tests during these visits and then record your results.

We will follow up with you every 3-to-6 months for up to 5 years to see how you are doing and if there have been any changes to your health.

You can take a survey online to see if you might be eligible and to have a study team member contact you: https://redcap.duke.edu/redcap/surveys/?s=34ELT8XKAY

Locations

Remote/online
Other

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

Yes

Study Details

Full Title

The American Lung Association Lung Health Cohort

Principal Investigator

Loretta
Que

Protocol Number

PRO00105522

Phase

N/A

Enrollment Status

OPEN TO ACCRUAL