Purpose of this Study
We are doing this study to see if an anti-oxidant pill called mitoquinol (mitoQ) might be helpful to control asthma.
Who Can Participate?
Eligibility
Adults age 18 and older who:
- Are diagnosed with asthma
- Do not smoke
- Are using a regular asthma controller (preventative) medication but still have asthma symptoms
- Have a BMI of 30 kg/m2 or higher
- Have not taken mitoquinol or a similar supplement like idebenone or co-enzyme Q10 in the last 8 weeks
For more information about who can join this study, please contact the study team at (919) 479-0861 or email DukeAirwayResearch@duke.edu.
- Are diagnosed with asthma
- Do not smoke
- Are using a regular asthma controller (preventative) medication but still have asthma symptoms
- Have a BMI of 30 kg/m2 or higher
- Have not taken mitoquinol or a similar supplement like idebenone or co-enzyme Q10 in the last 8 weeks
For more information about who can join this study, please contact the study team at (919) 479-0861 or email DukeAirwayResearch@duke.edu.
Age Range
18-80
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes
What is Involved?
If you choose to join this study, you will:
- Take a daily dose of the study supplement (mitoQ) or a placebo (inactive substance), in pill form, for 12 weeks
- Visit our clinic 6 times over 14 weeks
- Have your lung function tested
- Give blood and urine samples
- Answer questionnaires
- Keep a daily diary of your asthma symptoms
You can take a survey online to see if you might be eligible and to have a study team member contact you: https://redcap.duke.edu/redcap/surveys/?s=AART8KMF8J
- Take a daily dose of the study supplement (mitoQ) or a placebo (inactive substance), in pill form, for 12 weeks
- Visit our clinic 6 times over 14 weeks
- Have your lung function tested
- Give blood and urine samples
- Answer questionnaires
- Keep a daily diary of your asthma symptoms
You can take a survey online to see if you might be eligible and to have a study team member contact you: https://redcap.duke.edu/redcap/surveys/?s=AART8KMF8J
Locations
Other
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
Yes
Study Details
Full Title
MitoQ for the treatment of Metabolic Dysfunction in Asthma
Principal Investigator
Loretta
Que
Protocol Number
PRO00102278
NCT ID
NCT04026711
Phase
Pilot
Enrollment Status
OPEN TO ACCRUAL