Purpose of this Study
If you choose to join this study, you will:
- Have tumor tissue from a biopsy sent to a lab for genetic testing
-- If the tumor tissue has a genetic change that is targeted by one or more of the study drugs being tested in this study, you may be assigned to that study.
- Have tumor tissue from a biopsy sent to a lab for genetic testing
-- If the tumor tissue has a genetic change that is targeted by one or more of the study drugs being tested in this study, you may be assigned to that study.
Who Can Participate?
Eligibility
Children and adults with recurrent solid tumors, lymphoma, and CNS tumors who:
- Are 1-21 years of age
- Have no uncontrolled infection
- Have had a prior solid organ transplant
- Are 1-21 years of age
- Have no uncontrolled infection
- Have had a prior solid organ transplant
What is Involved?
We are doing this study to see if different study drugs or drug combinations that target specific genetic changes found in some cancers will shrink the tumor and/or prolong the time to progression.
Study Details
Full Title
APEC1621 NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Master Version Control Document
Principal Investigator
Jessica
Sun
Protocol Number
PRO00087722
NCT ID
NCT03213704
Phase
II
Enrollment Status
OPEN TO ACCRUAL