Antibiotic Prophylaxis in Rhinoplasty (Nasal Surgery)

Purpose of this Study

We are doing this study to find out if it is necessary to treat people with antibiotics after nasal surgery. We want to know if antibiotics are helpful or not during the healing process after surgery.

Who Can Participate?

Eligibility

Adults ages 18+ who are scheduled for nasal surgery.

For more information about who can join this study, please contact the study team at revital.benvenisti@duke.edu or 919-668-5328.

Age Range

18-110

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No

What is Involved?

If you choose to join this study, you will get a random assignment (like a coin flip) to 1 of 2 treatment arms in this study:<ul>
<li>If you are in Arm 1, you will get an antibiotic (either cefazolin or clindamycin) through IV (injected into a vein) during your surgery and not take any antibiotics on your own after surgery</li>
<li>If you are in Arm 2, you will get an antibiotic (either cefazolin or clindamycin) through IV (injected into a vein)</li></ul>
About a week after surgery, you will have a follow-up visit to see how you are doing. About 2 weeks after surgery, we will call you to see how you are doing.

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

No

Spanish Materials Available

No

Study Details

Full Title

Antibiotic prophylaxis in Rhinoplasty: A Randomized Controlled Trial

Principal Investigator

Charles
Woodard

Protocol Number

PRO00107781

NCT ID

NCT04194216

Phase

N/A

Enrollment Status

Open to Enrollment