Xenon MRI in ILD (Lung Disease & Healthy Volunteers)

Purpose of this Study

We are doing this study to learn how to get the best quality images of lungs in an MRI scanner as people breathe in Xenon gas. We hope this imaging will show key differences between diseased and healthy lungs.

Who Can Participate?

Eligibility

Adults ages 18+ who:
  • Are diagnosed with an interstitial lung disease; OR
  • Are in general good health and do not have lung disease (healthy, matching volunteers)
For more information about who can join this study, please contact the study team at cody.blanton@duke.edu.

Age Range

18-90

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes

What is Involved?

Description

If you join the study, you will:
  • Have 1 visit that will last 2-3 hours, with an optional second visit about 1 week later
  • Answer health questionnaires
  • Have your blood pressure, temperature, and breathing
  • Be scanned in an MRI machine while breathing in gas
  • Receive compensation for participation

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease

Principal Investigator

Joseph
Mammarappallil

Protocol Number

PRO00107570

NCT ID

NCT04855305

Phase

II

Enrollment Status

Open to Enrollment
ClinicalTrials.gov