Purpose of this Study
We are doing this study to understand how sex hormones (chemicals that tell cells and body parts to do certain things), such as estrogens and androgens, impact skin diseases like hidradenitis suppurativa (HS). To better understand this, we are enrolling both people who have diagnosed skin diseases and healthy volunteers who have no skin issues.
Who Can Participate?
Eligibility
Adults 18 years of age or older who:
<strong>If you are a candidate with skin disease</strong><ul>
<li>Are diagnosed with HS or any other skin condition that is currently active</li>
<li>Can independently complete surveys about your symptoms</li></ul>
<strong>If you are a healthy candidate</strong><ul>
<li>Are diagnosed with HS or any other skin condition that is currently active</li>
<li>Can independently complete surveys about your symptoms</li>
<li>Are willing to have skin biopsies</li></ul>
For more information about who can join this study, please contact the study team at <a href="mailto: connor.whatley@duke.edu"> connor.whatley@duke.edu.</a>
<strong>If you are a candidate with skin disease</strong><ul>
<li>Are diagnosed with HS or any other skin condition that is currently active</li>
<li>Can independently complete surveys about your symptoms</li></ul>
<strong>If you are a healthy candidate</strong><ul>
<li>Are diagnosed with HS or any other skin condition that is currently active</li>
<li>Can independently complete surveys about your symptoms</li>
<li>Are willing to have skin biopsies</li></ul>
For more information about who can join this study, please contact the study team at <a href="mailto: connor.whatley@duke.edu"> connor.whatley@duke.edu.</a>
Age Range
18-110
Looking for Healthy Participants
Yes
What is Involved?
If you choose to join this study, we will record demographic information such as your age, sex, race/ethnicity, and email address. We will also review your medical chart to find information that will be helpful in understanding your skin's health and condition.
At each visit, we will ask you to complete questionnaires in addition to collecting labs that include:
<li>Blood draws</li>
<li>Skin biopsies of normal and affected skin</li>
<li>Skin swabs</li>
<li>Skin tape stripping</li></ul>
At each visit, we will ask you to complete questionnaires in addition to collecting labs that include:
<li>Blood draws</li>
<li>Skin biopsies of normal and affected skin</li>
<li>Skin swabs</li>
<li>Skin tape stripping</li></ul>
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
Role of hormones in hidradenitis suppurativa and other skin diseases
Principal Investigator
Tarannum
Jaleel
Protocol Number
PRO00105932
Phase
N/A
Enrollment Status
Open to Enrollment