Directorio

217 clinical trials found.
Gastrointestinal Cancer

We are doing this study to see if the study drugs, LBL-007 plus tislelizumab in combination with bevacizumab plus capecitabine, are safe and effective for treating metastatic or unresectable colorectal cancer.

Compensation: No
Oncology
Brain and Spine Metastasis

We are doing this study to find the most effective and safe dose of an experimental drug called LY3537982 (the study drug) for people who have NSCLC that has KRAS G12C mutations.

Compensation: Yes
Ages: 18-100
Oncology
Duke University Hospital, Duke Raleigh Hospital
Cancer Immunotherapy

We are doing this study to find out if an experimental drug called LYL845 (the study drug) is a safe and effective treatment for your cancer. The study drug is custom-made for each participant from their own tumor tissue.

Compensation: No
Oncology
Genitourinary Cancer

We are doing this study to find out if an experimental drug called ABBV-CLS-484 (the study drug) is a safe and effective option for patients who have certain types of cancers that involve solid tumors, such as head and neck, lung, or kidney cancers. This study will also help determine what dose of the study drug works best when it is given either alone or in combination with pembrolizumab or cabozantinib.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called MGD024 (the study drug) is a safe and effective option for patients with different cancers of the blood or bone marrow that have relapsed or do not respond to standard therapy. We will test how the study drug works at different doses during this study in order to find the most effective dose.

Compensation: No
Oncology
Brain and Spine Metastasis

We are doing this study to learn if an MRI scan can find changes in the spinal cord that relate to pain.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental CAR-T cell therapy called MB-CART2019.1 (the study drug) may help eliminate cancer cells in patients who have relapsed or refractory DLBCL. The study drug will be combined with fludarabine and cyclophosphamide, which are both standard drugs used to treat DLBCL.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to compare 2 different treatment options for endometrial intraepithelial neoplasia (EIN) in the uterus. We want to find out if the combination of metformin and megestrol acetate can decrease the growth of EIN better than megestrol on its own. We will compare how well both options work for women who are planning to either have a hysterectomy or have an intrauterine device (IUD) placed.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital