Clinical Trials Directory

We are doing this study to find the most effective, safe dose of an experimental drug called rilvegostomig (the study drug). We want to know how well the study drug works on its own and when it is used in combination with another anti-cancer drug called datopotamab deruxtecan (also called Dato-DXd). We will compare how well both of these regimens work versus the standard treatment for non-small cell lung cancer (NSCLC) that is ctDNA-positive.

We are doing this study to find the safest and most effective dose of an experimental drug called Dato-DXd (the study drug) in patients with triple negative breast cancer (TNBC) and HER2-negative breast cancer.

We are doing this study to find out if an investigational drug called TYRA-300 (the study drug) is a safe and effective option for patients with locally advanced/metastatic urothelial cancer and other solid tumors.

We are doing this study to evaluate the safety and effectiveness of a drug called isatuximab when it is used in combination with lenalidomide and dexamethasone at lower doses. We want to know if this low dose combination can help patients with multiple myeloma achieve a better response while causing fewer or less severe side effects.

We are doing this study to better understand the unmet sexual health concerns of young adult male cancer survivors.

We are doing this study to find out if the combination of an investigational peptide (small protein) vaccine developed at Duke and a drug called vorasidenib is a safe and effective option for people with recurrent or progressive IDH1 mutant lower grade gliomas (brain tumors).

We are doing this study to find out the most preferred method among lung cancer patients for being connected to remote patient monitoring (RPM) devices. RPM devices are instruments that a patient can use to measure their own weight and vital signs. We want to find out if patients have an easier, more efficient time setting up these devices by using a virtual interface or with the assistance of a human agent.

We are doing this study to find out the practicality of using a new program called ViSPad on an electronic tablet. We want to know if this program can help reduce anxiety for cancer patients who are having imaging scans done (for example, MRI).