Clinical Trials Directory

168 clinical trials found.
Brain and Spine Metastasis

We are doing this study to find the best dose of the study drug, ABBV-400, and to see if it is a safe and effective option for treating cancer.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called ABBV-400 (the study drug) is a safe and effective option for treating various types of solid tumors.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called ABBV-453 (the study drug) is a safe and effective treatment for multiple myeloma. We want to identify the most appropriate dose and schedule to give patients the study drug.

Compensation: No
Oncology
Cancer Immunotherapy

We are doing this study to find out if the combination of 2 experimental drugs called C-TIL051 and NKTR-255 when they are given along with pembrolizumab is a safe and effective option for non-small cell lung cancer (NSCLC). C-TIL051 is custom-made for each participant from their own tumor tissue. Immune cells are isolated from your tumor tissue, regrown in a lab, and then formulated to be returned to your bloodstream. We want to know if C-TIL051 can help people's immune systems target and destroy cancer cells. NKTR-255 is designed to help C-TIL051 work better.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Radiation Oncology

We are doing this study to collect information about people with oligometastasis for future use.

Compensation: No
Ages: 18-110
Oncology
Remote/online
Radiation Oncology

We are doing this study to understand the benefit of using PET scan in addition to the standard of care CT scan to plan for radiation therapy. The PET-CT scan may allow your radiation doctor to fine tune the radiation plan or the delivery of radiation to your cancer.

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to find out if certain experimental drug combinations are safe and effective options for people who have recurrent or persistent endometrial cancer (cancer that has come back after treatment or does not respond to treatment).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Pediatric Cancer

We are doing this study to find out if carefully watching patients with low risk germ cell tumors after surgery will have different results than treating people with chemotherapy afer their surgery.

For people who are in standard risk groups related to germ cell tumors, we want to compare the effects of carboplatin with cisplatin and find out which of these drugs seems to work better.

Compensation: No
Oncology