Clinical Trials Directory

123 clinical trials found.
Skin Cancer - Melanoma

We are doing this study to find out if an investigational called Daromun (the study drug) is a safe and effective treatment for melanoma. We want to know if treating people with the drug before surgery to remove tumors can lower the chance of cancer recurrence.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called NT-I7 is a safe and effective treatment for people with LBL. The study drug will be combined with Kymriah, which is an approved, standard treatment for LBL.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called NT-17 is a safe and effective treatment for your cancer.

Compensation: No
Oncology
Skin Cancer - Melanoma

We are doing this study to compare different treatment options for people who have surgery to remove melanoma. We want to know if it is better to treat people with nivolumab alone after surgery, or if it is better to give people a combination of nivolumab and ipilimumab.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to compare two surgical procedures. We want to know if one procedure is better than the other in terms of lowering the risk of developing ovarian cancer for pre-menopausal women with BRCA1 mutations.

Compensation: No
Oncology
Gastrointestinal Cancer

We are doing this study to find out if a blood test for circulating tumor DNA (ctDNA) can provide information that might help doctors figure out the most appropriate therapy for patients with colon cancer after they have surgery.

Compensation: No
Oncology
Genitourinary Cancer

We are doing this study to find out if an investigational drug called apalutamide (the study drug) is a safe and effective treatment for your form of cancer. We want to know how well people respond to the usual therapy (hormone therapy and radiation) in combination with the study drug compared to the usual therapy on its own.

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital, Duke Raleigh Hospital
Genitourinary Cancer

We are doing this study to find out if 2 experimental treatments for high risk prostate cancer are effective compared to the usual treatments. For people with this form of cancer who also have a low gene risk score, we want to know if a short course of hormone treatment is as effective as the usual 24-month treatment. For people with a high gene risk score who will receive radiation, we want to know if adding a drug called apalutamide (study drug) to the usual treatment helps to slow the cancer's spread.

Compensation: No
Oncology