Clinical Trials Directory

123 clinical trials found.
Breast Cancer

We are doing this study to find out if an investigational drug called T-DM1 (the study drug) is an effective treatment for HER2+ breast cancer when it is given as part of a regimen with trastuzumab injections. We will compare this regimen to the standard treatment of paclitaxel and trastuzumab.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an investigational drug called TP-3654 (the study drug) is a safe and effective treatment for myelofibrosis. The study drug will be tested at different doses to find out what effects, if any, it has on myelofibrosis.

Compensation: No
Oncology
Breast Cancer

We are doing this study to try and find a way to detect breast cancer earlier or before it recurs.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Breast Cancer

We are doing this study to learn more about breast cancer and how it develops.

Compensation: Yes
Ages: 18-100
Oncology
Duke University Hospital, Duke Regional Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called CAP-100 (study drug) is a safe and effective treatment for people who have CLL or SLL that is not responding to standard treatments. We also want to know what dose of this study drug works best.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called CLR 131 (the study drug) is a safe and effective option for the treatment of multiple myeloma, certain lymphomas, and Waldenstrom's macroglobulinemia.

Compensation: No
Oncology
Genitourinary Cancer

We are doing this study to find out if an investigational drug called CG0070 (study drug) is safe and effective for patients who have NMIBC that does not respond to BCG treatment.

Compensation: Yes
Ages: 18-90
Oncology
Duke University Hospital
Genitourinary Cancer

We are doing this study to learn if a combination of chemotherapies and immunotherapies (carboplatin, cabazitaxel, nivolumab and ipilimumab) slows cancer growth in patients with metastatic neuroendocrine or aggressive variant prostate cancer.

We also want to learn about the types of side effects that patients have while they are taking these study drugs together.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital