Clinical Trials Directory

222 clinical trials found.
Breast Cancer

We are doing this study to find out if an experimental drug and device system called X-PACT is a safe and effective treatment for various forms of cancer.

Compensation: Yes
Ages: 8-110
Oncology
Duke University Hospital, Other
Genitourinary Cancer

We are doing this study to find out if an experimental drug called XmAb819 (the study drug) is a safe and effective treatment for clear cell renal cell carcinoma (ccRCC).

Compensation: No
Oncology
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called XTX101 (the study drug) is a safe and effective option for people who have advanced tumors or metastatic microsatellite stable colorectal cancer. We want to see how well it works on its own and in combination with a drug called atezolizumab.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to find the safest and most effective dose of an experimental drug called ZL-1310 (the study drug). We want to know if this drug can be beneficial for people with small cell lung cancer (SCLC) that progressed after at least one round of chemotherapy.

Compensation: No
Oncology
Head and Neck Cancer

We are doing this study to find the most effective, safe dose of an experimental drug called zanzalintinib (the study drug). We want to know how well it works in combination with pembrolizumab when it is given to people who have recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital, Duke Raleigh Hospital
Phase I

We are doing this study to find out what the safest and most effective dose of the study drug (ZN-A-1041) is when given alone or in combination with capecitabine.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital