PRECEDE (Cesarean C-Section Delivery)

Purpose of this Study

We are doing this study to find out if adding azithromycin to the routine single antibiotic preventative therapy can lower the risk of developing infections after a cesarean delivery.

Who Can Participate?

Eligibility

Adults ages 18+ who are pregnant and will be having a scheduled cesarean delivery at Duke University Hospital. For more information, contact the study team at jennifer.ferrara@duke.edu.

Age Range

18-110

Sex/Genders

Female (cisgender)
Non-binary or gender fluid
Looking for Healthy Participants
No

What is Involved?

Description

If you choose to join this study, you will get a random assignment (like a coin flip) to receive either azithromycin or placebo (normal saline) through your existing intravenous (IV) line that is placed before you have your baby. Study participation starts when you come to the hospital to deliver your baby and will end approximately 6 weeks after delivery.

Locations

Duke University Hospital

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

Azithromycin Prophylaxis for Prelabor Cesarean Delivery Trial

Principal Investigator

Brenna
Hughes

Protocol Number

PRO00115734

NCT ID

NCT06605118

Phase

III

Enrollment Status

Open to Enrollment