Cryocompression to Reduce Neuropathy Caused by Chemotherapy

Purpose of this Study

We are doing this study to find out if using ice with or without compression during chemotherapy can prevent neuropathy for patients being treated for gynecologic cancer.

Who Can Participate?

Eligibility

Adults ages 18+ who:
  • Are diagnosed with a gynecological cancer
  • Are receiving a taxane chemotherapy for the first time
  • Are scheduled to have at least 6 cycles of a taxane chemotherapy
  • Do not have pre-existing neuropathy
For more information about this study, please contact the study team at amelia.lorenzo@duke.edu.

Age Range

19-110

Sex/Genders

Female (cisgender)
Transgender male
Looking for Healthy Participants
No

What is Involved?

Description

If you choose to join this study, you will get a random assignment (like a coin flip) to either:
  • Get treatment with cryotherapy (ice packs) alone; OR
  • Get treatment with cryotherapy and compression
All participants will wear their ice packs on their hands and feet (with or without compression) for the duration of each of their chemotherapy infusions. Study team members will assist with setting up and taking off the wraps. We will ask a few questions at the start of the infusion about your neuropathy symptoms, and we will ask a few questions about your experience after the infusion is done.

Locations

Duke University Hospital
Duke Raleigh Hospital

Visit Timing

Weekdays

Compensation

No

Spanish Materials Available

Yes

Study Details

Full Title

Use of cryocompression to reduce chemotherapy-induced peripheral neuropathy in gynecologic cancer: a randomized controlled trial

Principal Investigator

Laura
Havrilesky

Protocol Number

PRO00106236

NCT ID

NCT04563130

Phase

N/A

Enrollment Status

Open to Enrollment
ClinicalTrials.gov