OPAL R01 (Chronic Pain Imaging Study)

Purpose of this Study

We are doing this study to compare activity in the brains of female adults who have chronic pain and/or use opioids to the brain activity of healthy female adults who are pain-free. We hope this study can help us develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

Who Can Participate?

Eligibility

Women ages 18+ who:
  • Have widespread pain that is medically documented (can be currently using opioids or not currently using opioids); OR
  • Are generally healthy and do not have any chronic pain conditions
For more information about who can join this study, please contact the study team at 919-684-2758 or chronicpainresearch@duke.edu.

Age Range

18-65

Sex/Genders

Female (cisgender)
Looking for Healthy Participants
Yes

What is Involved?

Description

If you choose to join this study, you will:
  • Come in for 1 or 2 study visits to our clinic that last up to 4.5 hours
  • Have MRI scans
  • Play cognitive games during your study appointment
  • Have sensory testing
  • Have blood draws
You can sign up for us to contact you here: https://redcap.duke.edu/redcap/surveys/?s=RXCMMCPWNKWJELN4

Locations

Duke University Hospital

Visit Timing

Weekdays
Weekends

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

Neuroimaging of Opioid Phase

Study Website

Study Website

Principal Investigator

Katherine
Martucci

Protocol Number

PRO00110253

NCT ID

NCT05905419

Phase

N/A

Enrollment Status

Open to Enrollment
ClinicalTrials.gov