OPAL R01 (Chronic Pain Imaging Study)

Purpose of this Study

Participants will attend 1 or 2 study visits that last up to 4.5 hours. During the visits, they will have MRI scans, play thinking and memory games, complete sensory tests, and provide blood samples. Researchers will use this information to learn more about brain and body function. You can sign up for us to contact you here: https://redcap.duke.edu/redcap/surveys/?s=RXCMMCPWNKWJELN4

Who Can Participate?

Eligibility

Participants may be able to join if they are women age 18 or older with medically documented widespread chronic pain. They may be currently using opioids or not using opioids. Researchers will compare their brain activity with that of healthy women who do not have chronic pain. For more information about who can join this study, please contact the study team at 919-684-2758 or chronicpainresearch@duke.edu.

Age Range

18-65

Sex/Genders

Female (cisgender)
Looking for Healthy Participants
No

What is Involved?

Description

This study is comparing brain activity in adult women with chronic pain or who use opioids to brain activity in healthy women without pain. Researchers hope this information will help create better treatments for chronic pain and provide alternatives to opioid medicines.

Locations

Duke University Hospital

Visit Timing

Weekdays
Weekends

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

Neuroimaging of Opioid Phase

Principal Investigator

Katherine
Martucci

Protocol Number

PRO00110253

NCT ID

NCT05905419

Phase

N/A

Enrollment Status

Open to Enrollment