EXPAND: Safety and Efficacy of the 10 GE Xenokidney

People can join this study if they are adults who need a kidney transplant and have a high chance of dying without one within five years, or if they have a very high level of antibodies that makes it very hard to find a donor kidney. They must also have a body weight level within a certain range based on BMI. People cannot join if they have serious health problems that could make the transplant unsafe. These can include severe blood vessel disease, serious heart problems, lung disease, uncontrolled diabetes, or high blood pressure in the lungs. They also cannot join if they have certain infections such as hepatitis or HIV, a history of tuberculosis, a non kidney cause of anemia, or major mental health conditions that required hospitalization.