Purpose of this Study
Taking part in this study involves one visit that lasts about thirty minutes. During the visit, participants will answer a short survey about their health and hearing. They will also give a small saliva sample and have a gentle swab placed in the nose. These steps do not hurt. The visit can be done in person at a clinic or another location, or sometimes from home if the person lives nearby. There is no cost to take part, and there is no payment for joining the study.
Who Can Participate?
Eligibility
People can join this study if they are 3 years old or older. They may have a condition with a different number of sex chromosomes, such as Turner syndrome, Klinefelter syndrome, Triple X, or XYY, or they may have typical chromosomes and join as a comparison volunteer. They cannot join if they are currently sick with a fever or have an ear infection. They must be able to complete a short visit either in person or from home if they live nearby. Children who are younger than 18 must have a parent or guardian give permission.
Age Range
3-110
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes
What is Involved?
Description
This study looks at how differences in sex chromosomes affect hearing. Some people are born with an extra or missing sex chromosome, and this can change how the body develops. Researchers want to learn if these differences can also affect hearing health. By understanding this better, doctors hope to give better care and support to people with these conditions.
Locations
Other
Visit Timing
Weekdays
Compensation
No
Spanish Materials Available
No
Study Details
Full Title
Examining Chromosome-linked Hearing Outcomes (ECHO): A Cross-sectional Study of Hearing Health, Genomic Profiles, and Pathogen Susceptibility Across Sex Chromosome Complements
Principal Investigator
Adrianna
San Roman
Protocol Number
PRO00120390
Phase
N/A
Enrollment Status
Pending Open to Enrollment