Clinical Trials Directory

217 clinical trials found.
Radiation Oncology

We are doing this study to understand the benefit of using PET scan in addition to the standard of care CT scan to plan for radiation therapy. The PET-CT scan may allow your radiation doctor to fine tune the radiation plan or the delivery of radiation to your cancer.

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to find out if certain experimental drug combinations are safe and effective options for people who have recurrent or persistent endometrial cancer (cancer that has come back after treatment or does not respond to treatment).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Pediatric Cancer

We are doing this study to find out if carefully watching patients with low risk germ cell tumors after surgery will have different results than treating people with chemotherapy afer their surgery.

For people who are in standard risk groups related to germ cell tumors, we want to compare the effects of carboplatin with cisplatin and find out which of these drugs seems to work better.

Compensation: No
Oncology
Brain and Spine Metastasis

We are doing this study to find out if a new experimental drug called NVL-655 (the study drug) is a beneficial option for people with NSCLC.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to research the genes of patients with lung cancer that has been or will be removed by surgery for a chance to get treatment in a clinical trial.

Compensation: No
Oncology
Brain and Spine Metastasis

We are doing this study to learn if a new study drug called AMG-509 is safe and effective in men who have metastatic, castrate-resistant prostate cancer. AMG-509 is a type of drug that helps a type of immune cells called T cells find and kill prostate cancer cells.

The first part of this study will test different doses of AMG-509 in men to learn what side effects the study drug causes and which doses are safe. The second part of the study will see if a safe dose of AMG-509 slows cancer growth.

This study will also teach us how long AMG-509 stays in your body, and whether treatment with AMG-509 changes the genes and proteins found in your tumor cells.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out how an experimental drug called sotorasib works in your body and against your cancer. We will compare how this drug works alone and in combination with several different drugs.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to compare how safe and effective different drug combinations are for treating metastatic cancer.

Compensation: No
Oncology