Purpose of this Study
We are doing this study to compare two different screening mammography methods in pre- and post-menopausal women to understand whether one method is better than the other at finding life-threatening breast cancers.
Who Can Participate?
Eligibility
Women ages 45-74
Age Range
40-110
Sex/Genders
Female (cisgender)
Looking for Healthy Participants
Yes
What is Involved?
If you choose to join this study, you will get a random assignement (like the flip of a coin) to screening with Tomosynthesis Mammography (TM) or Digital Mammography (DM) .
The frequency and number of screening mammograms will vary with your menopausal status and whether you have breast cancer risk factors.<ul>
<li>All premenopausal women will have annual screening</li>
<li>Postmenopausal women will have screening every 2 years unless they have any specific risk factors</li>
<li>All participants will be followed for 4.5 to 8 years</li></ul>
The frequency and number of screening mammograms will vary with your menopausal status and whether you have breast cancer risk factors.<ul>
<li>All premenopausal women will have annual screening</li>
<li>Postmenopausal women will have screening every 2 years unless they have any specific risk factors</li>
<li>All participants will be followed for 4.5 to 8 years</li></ul>
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
No
Spanish Materials Available
No
Study Details
Full Title
EA1151: Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
Principal Investigator
Lars
Grimm
Protocol Number
PRO00086885
NCT ID
NCT03233191
Phase
III
Enrollment Status
Open to Enrollment