If you choose to join this study, you will go through a screening period to find out if you are eligible. During this screening period, you will:

• Have a physical exam
• Have a heart scan (ECG)
• Have blood draws
• Have bone marrow samples taken
• Have imaging (X-ray, CT scan or PET/CT)

If you are eligible to continue in the study after screening, you will:

• Check into the hospital for at least 8 days to begin the study therapy
• Get an infusion (through IV) of Kymriah the day after you check in
• Check into the hospital again for about 24 hours approximately 3 weeks after receiving Kymriah
• Get an injection (shot) of the study drug when you check in for this second admission

When you are not staying in the hospital, you will need to stay within a 1-hour drive of Duke during the time between the two hospital admissions and for 4 weeks after the second hospital admission. We will schedule you to come in for 3 follow-up visits after your study drug injection to see how you are doing.