Clinical Trials Directory

403 clinical trials found.
Gastrointestinal Cancer

We are doing this study to see if an experimental drug called RMC-6236 (the study drug) is a safe and effective option for treating colorectal or pancreatic cancer when it is combined with different chemotherapy drugs.

Compensation: No
Oncology

We are doing this study to compare 2 different procedures for treating cervical cancer and find out which approach has the best outcomes for patients. The two procedures that we will compare are open surgery with a single large incision (laparotomy) and robotic assisted laparoscopy (small incision surgery). We do not know which option is preferable in most cases, and we hope this study can help us find out which procedure is the better choice for patients.

Compensation: No
Ages: 18-110
Duke University Hospital, Duke Raleigh Hospital
Lungs and Breathing

We are doing this study to find out if an investigational drug called belumosudil (the study drug) is an option for the treatment of chronic lung allograft dysfunction (CLAD). The study drug is taken by mouth.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Skin, Hair and Nails

We are doing this study to find out how effective an experimental drug called rocatinlimab (the study drug) is for people who have moderate-to-severe atopic dermatitis. This study is a continuation of 2 previous clinical trials we conducted for this same study drug: the ROCKET-Horizon and the ROCKET-Astro clinical trials.

Compensation: No
Non-Oncology
Research for Children and Teenagers

We are doing this study to find out if an experimental drug called rocatinlimab (the study drug) is a safe and effective option for adolescents with atopic dermatitis (eczema).

Compensation: Yes
Ages: 12-18
Non-Oncology
Other
Research for Healthy Adults

We are doing this study to understand how sex hormones (chemicals that tell cells and body parts to do certain things), such as estrogens and androgens, impact skin diseases like hidradenitis suppurativa (HS). To better understand this, we are enrolling both people who have diagnosed skin diseases and healthy volunteers who have no skin issues.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to determine the effect of single vs multiple arterial revascularization (this is the restoration of blood flow to an organ) for female patients undergoing coronary artery bypass surgery (CABG).

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an investigational drug called OBI-3424 is a safe and effective option for patients with leukemia or lymphoma.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital