Clinical Trials Directory

38 clinical trials found.

We are doing this study to find out if an investigational vaccine (HydroVax-005 CHIKV - the study vaccine) is a safe and effective option to protect against chikungunya virus. Chikungunya virus is spread by mosquitos that are most common in Africa, Asia, and India. Infection with the virus can cause serious disease in older adults, children, and people with weaker immune systems.

Compensation: Yes
Ages: 18-49
Other
Research for Children and Teenagers

We are using you or your child's medical information in this study to better understand the diagnosis, treatment, and complications of Spina Bifida.

Compensation: No
Ages: 0-110
Non-Oncology
Remote/online, Duke University Hospital
Brain, Spinal Cord and Nerves

We are doing this study to learn more about the rare diagnosis of New Daily Persistent Headache (NDPH). We want to get more information about why some children and young people develop this condition and how it is different from traditional headaches, like migraines. This knowledge can help us to begin developing possible treatments for NDPH.

Compensation: No
Ages: 12-18
Non-Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We are doing this study to collect information about the speeds of eye and head movements in healthy children and young adults. This information will help us establish normal values related to these movement speeds and patterns. If we have a measure of what is normal, this will help us determine the severity of symptoms or injury for people who are treated for concussions.

Compensation: Yes
Ages: 12-25
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Pickett Road Research, Other
Brain, Spinal Cord and Nerves

We are doing this study to compare activity in the brains of female adults who have chronic pain and/or use opioids to the brain activity of healthy female adults who are pain-free. We hope this study can help us develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

Compensation: Yes
Ages: 18-65
Non-Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to find out if we can identify biomarkers that indicate the presence of ovarian cancer or indicate that it is likely to develop. Biomarkers are substances that can be released from cancer cells into the blood and can provide information on the following things: changes to someone's genes or DNA, how cancer cells will respond to cancer treatment, and whether cells are becoming resistant (no longer responding) to cancer treatment.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Remote

We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease.

*The study drug is a statin, which is usually used to help lower cholesterol levels.

Compensation: Yes
Ages: 75-110
Non-Oncology
Pickett Road Research, Kannapolis, Other
Bones, Joints and Muscles

We are doing this study to get a better understanding of how exercise affects the motion and mechanics of the shoulder joint in people who have shoulder instability and are planning to have shoulder surgery. We hope the information we gain from this study can improve treatment methods for injuries like shoulder dislocations or rotator cuff tears.

Compensation: Yes
Ages: 15-35
Non-Oncology
Duke University Hospital, Other