Clinical Trials Directory

168 clinical trials found.
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called iberdomide (the study drug) is a safe and effective option for multiple myeloma (MM). We also want to what the most appropriate dose and timing for taking the study drug should be.

Compensation: No
Oncology
Genitourinary Cancer

We are doing this study to find out if an investigational drug called CG0070 (the study drug) is safe and effective for patients who have NMIBC that does not respond to BCG treatment.

Compensation: Yes
Ages: 18-90
Oncology
Duke University Hospital
Genitourinary Cancer

We are doing this study to learn if a combination of chemotherapies and immunotherapies (carboplatin, cabazitaxel, nivolumab and ipilimumab) slows cancer growth in patients with metastatic neuroendocrine or aggressive variant prostate cancer.

We also want to learn about the types of side effects that patients have while they are taking these study drugs together.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Breast Cancer

If you choose to join this study, you will:<ul>
<li>Give a saliva sample</li>
<li>Have a genetic test using the Color Genomics 30 gene hereditary panel test</li></ul>

Compensation: No
Ages: 18-110
Oncology
Remote/online
Gynecologic Cancer

We are doing this study to find out if neratinib combined with palbociclib is better than neratinib alone when it comes to treating HER2-positive tumors.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Breast Cancer

We are doing this study to find out if adding a drug called tucatinib to the usual treatment of T-DM1 on its own can help prevent breast cancer from returning.

Compensation: No
Oncology
Gastrointestinal Cancer

We are doing this study to compare the study drug, lutetium-177 edotreotide, to existing standard-of-care therapies.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Primary Brain and Spinal Cord Tumors

We want to find out if a study drug called larotrectinib is an effective treatment for brain tumors in children and young adults. We want to learn how well it works to shrink brain tumors when used alone or when given with standard chemotherapy or after radiation therapy.

Compensation: No
Ages: 0-21
Oncology
Duke University Hospital