Clinical Trials Directory

123 clinical trials found.
Gastrointestinal Cancer

We are doing this study to collect information about how well dabrafenib plus trametinib works in patients who have unresectable (cannot be removed by surgery) or metastatic BRAF V600E mutation positive solid tumors.

Compensation: No
Oncology
Skin Cancer - Melanoma

We are doing this study to find out if the combination of the drugs Dapansutrile and Pembrolizumab is a safe and effective treatment for people with melanoma that does not improve after PD-1 therapy.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to see if the study drugs, domvanalimab and zimberelimab, are safe and effective for treating advanced or metastatic gastroesophageal adenocarcinoma.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out how well an experimental drug called DSP-5336 (the study drug) works in people with AML or ALL.

Compensation: No
Oncology
Gastrointestinal Cancer

We are doing this study to learn more about Gastric or Gastroesophageal Junction Cancer.

Compensation: No
Ages: 18-110
Oncology
Remote/online
Skin Cancer - Melanoma

We are doing this study to compare the safety and effects of stopping the standard melanoma treatments of nivolumab + pembrolizumab or nivolumab + relatlimab at different times. We hope this study will help us discover certain markers from imaging and biopsies that can signal when it is the appropriate time to stop therapy.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out whether an autotransplant improves survival in mantle cell lymphoma patients who have achieved an excellent (minimal residual disease-negative) first complete remission (CR).

Compensation: No
Oncology
Breast Cancer

We are doing this study to find out if a new vaccine (ESR1 peptides) is safe and if they will help people with Estrogen receptor positive (ER+) breast cancer.

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital