Clinical Trials Directory

222 clinical trials found.
Thoracic Cancer

We are doing this study to compare the usual treatment of Nivolumab and ipilimumab to using the usual treatment plus surgery for people with sarcomatoid mesothelioma. We want to find out if adding surgery to the immunotherapy regimen is effective in stabilizing this type of cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Cancer Prevention and Screening

We are doing this study to test a new strategy to help people quit smoking. We want to know if the study approach is better than the usual approach. The usual approach is to encourage patients to quit smoking using cessation support manuals and either medication or nicotine replacement products. We want to know if the study approach works better for cancer survivors who live in rural areas.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Other
Brain and Spine Metastasis

We are doing this study to find the best dose of the study drug, ABBV-400, and to see if it is a safe and effective option for treating cancer.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called ABBV-400 (the study drug) is a safe and effective option for treating various types of solid tumors.

Compensation: No
Oncology
Thoracic Cancer

We are doing this study to find out if the combination of 2 experimental drugs called C-TIL051 and NKTR-255 when they are given along with pembrolizumab is a safe and effective option for non-small cell lung cancer (NSCLC). C-TIL051 is custom-made for each participant from their own tumor tissue. Immune cells are isolated from your tumor tissue, regrown in a lab, and then formulated to be returned to your bloodstream. We want to know if C-TIL051 can help people's immune systems target and destroy cancer cells. NKTR-255 is designed to help C-TIL051 work better.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Radiation Oncology

We are doing this study to collect information about people with oligometastasis for future use.

Compensation: No
Ages: 18-110
Oncology
Remote/online
Cancer Immunotherapy

We are doing this study to find out if an experimental drug called ADP-A2M4CD8 (the study drug) is a safe and effective option for your cancer when it’s given alone or in combination with nivolumab. The study drug is custom-made for each participant from their own white blood cells or T-cells. We collect these cells using a procedure called leukapheresis.

Compensation: No
Oncology
Gynecologic Cancer

We are doing this study to find out if certain experimental drug combinations are safe and effective options for people who have recurrent or persistent endometrial cancer (cancer that has come back after treatment or does not respond to treatment).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital